The older Space Explorer is the one I have with the wrist pad. It's difficult to show, but my palm rests on the rubber pad at the base. My palm probably rests at about a 30 degree angle naturally. Overall, it feels very comfortable. Sometimes the buttons are a little goofy to reach though. I haven't tried the sideways "Good wrist position".
The "travel" space navigator is shown below. The position is just awkward to me. I have felt irritation in my wrist with this device.